Imagine being able to take a pill instead of daily injections! Thanks to scientists from Australia and Norway, this could soon become a reality. They have developed a smart insulin in tablet form that activates only when blood sugar levels rise.
A smart pill that knows when to act
This innovative pill uses nanocarriers—microscopic particles—that protect insulin until it reaches the liver. When these nanocarriers detect high glucose levels, they release insulin in a targeted, safe way without the risk of low blood sugar (hypoglycemia).
"Insulin is released quickly when sugar is high, but not when it is low," explained Dr. Nicholas Hunt from the University of Sydney.
No injections and no stress!
This method of administration has many advantages:
- No needles – ideal for children and those afraid of injections.
- No need for refrigeration – convenient for travel and warmer climates.
- Fewer side effects – insulin works exactly where it’s needed, not throughout the entire body.
Successful animal testing
The pills have already been successfully tested on mice, rats, and 20 healthy baboons. The insulin lowered blood sugar without hypoglycemia, side effects, or weight gain. The baboons were even given the pill with sugar-free chocolate – and it worked perfectly.
Human trials begin this year!
Clinical trials on humans will begin during 2025. The first phase will test safety and potential side effects, particularly in people with and without type 1 diabetes. If the results are similar to those from animal testing, it could be a major breakthrough in diabetes treatment.
Conclusion
Smart pill that releases insulin only when needed could transform life for people with diabetes.
Although still in the early stages, scientists and patients worldwide are eagerly awaiting the next phase of research.
